Introducing Simplifica: mathematical models and AI for digital health
Bio4Dreams and FAST Computing announce the launch of Simplifica, a new innovative startup and Benefit Corporation based in Trieste, created to revolutionize the analysis of clinical and healthcare data through the combined use of advanced mathematical models and artificial intelligence.
Simplifica’s mission is to give meaning to clinical data collected by hospitals and regional healthcare information systems, which today are often underutilized or fragmented. The goal is to support diagnosis and care pathways and to design innovative prevention programs.
Starting from already available clinical data, the startup aims to develop modular, interoperable digital platforms that enable predictive and personalized analyses, designed to be user-friendly. These solutions will easily integrate into existing workflows and offer intuitive dashboards—also for non-technical users—delivering clear, actionable insights.
Simplifica targets institutions, public bodies, public and private hospitals and care facilities, as well as pharmaceutical and biotech companies, startups, and SMEs operating in the health sector.
The startup brings together the expertise of FAST Computing—a SISSA mathLab spin-off specialized in mathematical modeling, predictive algorithms, and data analysis—with Bio4Dreams’ extensive experience in building innovative startups focused on health and life sciences.
As part of its launch, Simplifica has entered a customized acceleration and incubation program within the Bio4Dreams ecosystem.
“Bio4Dreams aims to strengthen its ecosystem and portfolio startups through the adoption of cutting-edge technologies, including AI applied to healthcare. Simplifica was born from this strategic vision: a synergistic initiative that combines the expertise of FAST Computing and Bio4Dreams, enhancing the strengths of both.”
Elisabetta Borello, Co-Founder, VP Strategy & External Relations of Bio4Dreams
“With the launch of Simplifica, we aim to broaden our reach in the health and well-being sector, a key focus area for FAST Computing. Bio4Dreams is the natural and essential partner to help us achieve Simplifica’s goal: to unlock the value of clinical and healthcare data and deliver a positive impact on people’s health through innovative mathematical model-based technologies.”
Andrea Martini, Co-Founder & CEO of FAST Computing
📗 Learn more about Simplifica and other startups in our portfolio.

